Endocrine Abstracts

Introduction: Autotaxin (ATX)[Ectonucleotide Pyrophosphatase /Phosphodiesterase family member 2 (ENPP2)] is a lysophospholipase D stimulating cell migration, metastasis and angiogenesis. ATX hydrolizes lysophosphatidylcholine (LPC) and produces bioactive lysophosphatidic acid(LPA). There are some clues about ATX–LPA pathway modulation may unlock the gate of metabolic derangement including diabetes formation or may impact formation of cardiovascular diseases via LPA’s...

Introduction: Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumor type. They are usually recognized after they cause symptoms especially when tumor size increases and eventually invades adjacent structures. Nevertheless the discovery would also be accidental. In the literature some kind of gender difference is reported in NFA’s behavioral results such as pituitary axis deficits or consequences of surgery however they resulted with contr...